1. The problem is a USB Webcam Microphone does not work in Skype for Linux

2. Disable PulseAudio
# nano -w /etc/pulse/client.conf
autospawn = no
# systemctl reboot

3. May be one must to init ALSA
# alsactl init

4. If you are a KDE5-Plasma user, then install proper mixer
# apt install kmix

5. Do "ls -l /dev/snd/" and then play a sound file to detect what a card.device pair is proper
$ mplayer -ao alsa:device=hw=1.0 /path/to/file.mp3
(where 1 is a card number, 0 is a device number)

6. Setup Skype for properly Audio Device & do Echo Test Sound Service call

7. Set default ALSA device to enable sound in your browser
# nano -w /usr/share/alsa/alsa.conf
defaults.ctl.card 1
defaults.pcm.card 1
defaults.pcm.device 0
(where 1 is a card number, 0 is a device number)

8. Profit